ABOUT STEM 2010

WE are happy to share with you the proceedings of STEM 2010 which is organized every year under the umbrella of the Society of Regenerative Medicine and Tissue engineering (SRMTE, www.srmte.org). This year it was held in GOA, in the International centre, on 31st January-1st February 2010, jointly with the Government of Goa. The chief sponsors for the event was International Stemcells Ltd (ISSL) and SR Biotechnologies (research and development partner). We also had corporate sponsors like Millipore who strengthened their position with us by supporting the society meeting. The event was graced by the Vice Chancellor of the Goa University, who inaugurated the event. We had eminent speakers from the field of stem cells both basic and translational and clinicians.

STEM 2010 started off with a huge bang and was supported by all the delegates including our student body, who had come to attend our conference. The society was incepted in 2004 and the community is growing with members from all walks of life. Students, stem cell biologists, doctors, tissue engineers and the likes find a common platform to converge and merge, and forge ahead with newer reinforced mission to bring forth stem cell therapy in
new forms, always.



Dr. S.G.Ananda.Rao,Chairman, Director
ISSL, at STEM 2010.











Inaugural speech by Dr.Dilip
Deobakar






Inauguration of STEM 2010







The meeting kicked off with the VC of Goa University taking us back in time, when stem cell application was still a fairy tale, and definite steps towards applying 7the thought was still in shrouds.





Dr. Gururaj.A.Rao, Director ISSL, at the meeting.







Our Chairman Director Dr.

S.G.Ananda.Rao felicitating Dr.

Rajendran.









Life sciences students attending

STEM 2010.







ISSL Banner at the venue, International

Centre, GOA.






Our Delegates at STEM 2010.








Our Team at STEM 2010.






Stem cell therapy requires an amalgamation of basic sciences with clinical practioners for which, ISSL strives in joining hands with leading experts in bringing together therapy options in areas of several untreatable diseases. ISSL is the first company in India, who is giving you banking to therapy option.

AS you have committed yourself into this family by banking with us, you are now a part of this tumultuous journey with us, where our sole aim is to offer you therapy options with stem cells in treating certain diseases which could be otherwise not possible. This will make it worthwhile that you have banked your precious child’s stem cells with u We as a company realize our responsibility towards our bankers to keep you abreast with the latest on stem cell application. We also are proud to share with you the clinical research we have done in our company to make stem cell application a reality.

We hope that, by building bridges in certain disease types, we are keeping abreast with the latest in stem cell therapy, and you can avail the therapy options from us. Please contact us if you know anyone who is looking for a therapy option is stem cells in diseases like:
Late stage peripheral occlusion (Ischemic limb).

Non healing wounds.

Diabeteic Foot ulcer.

Diabetic neuropathy.

Non healing fractures.

Chronic Liver failure.

Spinal Cord Injuries.

Multiple Sclerosis. (Clinical Trial ongoing)

Ischemic Heart Disease.

Chronic Kidney Disease (including Diabetic nephropathy) Osteo arthritis.

Cancer therapy. Muscular Dystrophy.
HAVE NOT BANKED YOUR STEM CELLS?????

Do not worry as ISSL is proud to offer you banking options for you as well. You can bank your stem cells from your LIPOASPIRATES. We are proud to say that we are the leaders in stem cell therapy options, not only with cord blood but also with bone marrow, lipo derived cells and cord derived mesenchymal cells. PLEASE CONTACT US FOR FURTHER DETAILS.

Streamline stem cell treatment: Expert

PANAJI: There is a need to regulate stem cells that are injected into a patient's body and used in therapy, said International Stemcell Services Limited chairman Dr S G A Rao.

Speaking to the media on the sidelines of the sixth annual conference on biotechnology organized by Society for Regenerative Medicine and Tissue Engineering on Sunday, Rao said that stem cell treatment in India needs to come under a regulatory framework.

"It is only the guidelines have been formulated. But till they are incorporated into an Act, there will be no checks on stem cell treatment in the country. If someone has a complaint, the government has no power to act on it", said Rao.

Incidentally, stem cell treatments are a type of therapy that introduce new cells into damaged tissue to treat a disease or injury. Stem cell banks store blood and frozen tissue samples for research and surgery.

Recently, an Indian doctor had come under fire for making claims of treating incurable or terminal illnesses using embryonic stem cells without any safety trials and randomized clinical studies. It was claimed that she had been charging as much as 30,000 pounds for a course of treatment.

In another instance, an ophthalmologist from South India collected 5 ml blood from the patient's arm, and claimed to separate the stem cells and inject the same back into the patient.

"Such quacks, who charge exorbitant prices for unproven and dangerous treatment, survive as there are no regulations. There are no stem cells in the blood," said Dr Rao.

Over the last few years, India has witnessed a tremendous growth in the stem cell business. Apart from many foreign companies, the industry has witnessed the mushrooming of small domestic players.

Why ISSL ?

Why should you choose us?

At International Stem cell Services, we are always committed to your well-being and strive to bring to you the very best service whether it is stem banking, stem cell therapy and stem cell storage. We have always maintained the highest standards so you can be rest-assured that you are in safe hands. Here are some more things to consider when weighing your options for stem cell storage and therapy.

Our Experience

International Stem cell Services is based upon strong fundamentals with more than 50 years of combined experience in stem cell-related research and stem cell storage in india. Dr. S. G. A. Rao, the CMD of International Stem cell Services is a pioneer in stem cell research and has spear-headed the stem cell revolution in India. In addition, our scientific team also comprises of experts in a number of related disciplines including immunology, tissue engineering, and gene therapy.

Commitment

Formed in 2003, International Stem cell Services is the longest running autologous banking company in India. Till date we have stored more than 5000 cord and cord blood units.

Giving you more banking options

Only at International Stem cell Services you have the option of storing stem cells, both cord blood storage as well as umbilical cord stem cell storage itself. Umbilical cord storage and cord blood storage provide an excellent source of hematopoeitic progenitor stem cells while the umbilical cord blood offers a valuable source of mesenchymal stem cells. In addition, we offer unique services such as stem cell expansion. To know more about the potential of stem cells, please visit our Learning center.

Pioneering stem cell therapies

From the very beginning we have always strongly believed that the value of stem cells can be realized only when scientifically and clinically sound stem cell therapies applications are available. Therefore, instead of focusing only on banking, we have always shared our scientific expertise in stem cells with various clinicians to develop clinically relevant protocols for a number of diseases. In the past year we have been successful in conducting several stem cell clinical trials pertaining to disease conditions like Chronic Liver Disease, Myocardium infarction, spinal cord injury, osteoarthritis, including the world’s second largest trial in Buerger’s disease.

Financial stability

International Stem cell Services is a financially sound company which is debt-free so you do not have to worry about losing your child’s cells at any time. Moreover, we guarantee that you will have access to the cells you store with us.

Control of processing and storage

Instead of relying on third-party technology to process and store cord blood, At International Stem cell Services, we utilize our vast in-house experience and has full control over the processes of stem cell storage and umbilical cord storage that determine the reliability of the final product.

Reliability

Since its inception, International Stem cell Services has helped more than a hundred people by providing cGMP grade stem cells for treating a number of different diseases. We have consistently achieved a 100% record in safety and efficacy.

Value

We are deeply committed to providing our quality services at the most affordable price to you. Our stem cell storage service cost is still thousands of rupees lower than our competitors.

Personalized service

We are the only company in India that provides a dedicated, personalized service to you. Our local representatives will be available to you at every step of the way. You will not have to rely on unpredictable courier services that may lead to the loss of your baby’s valuable possession.

Special benefits of banking with International Stem cell Services

Referral Program
Once you are a part of our family, please best rest assured that we take care of all your requirements in the area of stem cells ie from banking to therapy. In this regard, you could refer our company to your friends and relatives for banking and therapy services. In doing so, we will return the gesture by including you in our referral program which will include a referral fee or a break for therapy procedure involving our company.

Stem Cell Expansion Services
As we are a knowledge based company, research and training are vital components. The logical research interest for us is in stem cell expansion .and providing the same to our clients. We have patents ( ongoing) on several protocols in hematopoietic as well as mesenchymal stem cells.

Sibling Donor Program

Families with one beta Thalassaemic child can bank cord blood stem cells from their subsequent child for transplant purposes. This service has found itself very relevant ot parents who have the older child suffering from hematopoietic disorders, which could be easily treated if they would store the next /subsequent child’s cord blood stem cells. We are very actively promoting this concept and we also offer special rates for such parents. As our motto is banking to therapy, we will make sure that we go hand in hand with our clients till the last lap

STEM 2010 - 6TH ANNUAL CONFERENCE ON BIOTECHNOLOGY

CONFERENCE OVERVIEW

STEM 2010 CONFERENCE will bring people who are working in the field of Stem cell Research leading towards Stem Cell therapy. It will give ample scope to interact with leading personalities in this field. This field of research in stem cell biology would lead to possible treatment of presently incurable diseases like Spinal cord injury, Parkinson, diabetic, cancer, generic diseases etc.

Stem Cell research is a very frontline subject at this moment all over the world, and scientist working in this area will get an opportunity to come together at this conference and share their findings and brainstorm on this subject which will lead to future path in India.

Conference was held in Goa from Jan 31 st Feb 1st and more than 10 reputed companies have attended the conference. To name the few,

• International Stemcell Services Ltd
• S R Biotechnologies Pvt Ltd
• Avesthagen
• Indus Instruments Impex Pvt Ltd
• Stem Life, Malaysia
• Bio Informatics Institute, Singapore
• Stemcyte Therapeutics India Pvt Ltd
• Kokilaben Dhirubhai Ambani Hospital
• ReeLab
• Cytori Therapeutics
• Axis Bank
• BD BioSciences
• Millipore India
• Emprocells
• Cell Bios

Clinical Trial at ISSL

Clinical Trials

Disease	Clinical partner and location	No. of patients	Results
Buerger’s Disease	Dr. K. R. Suresh/ Bhagawan Mahavir Jain Hospital, Bangalore	45	Safety and Efficacy established. Published in Journal of Vascular Surgery, December 2008 – Pubmed link
Chronic Liver Failure	Dr. C. M. Habibullah/ CLRD, Hyderabad	5	Safety and efficacy established. Published in Tranplantation Proceedings – Pubmed link
Spinal Cord Injury	Dr. Arvind Bhateja/ Sita Bhateja Specialty Hospital, Bangalore	5	Safety established.
Osteoarthritis	Dr. Rudraprasad/ Isha - International Stem cell Services Therapy Center, Bangalore	5	Safety established.
Muscular Dystrophy	Dr . Jayarajan/Ayurvedagram	5	Safety established.
Myocardial infarction	Trinity Hospital	4	Safety established

We are offering treatment for: Diabetes, Parkinson’s, non healing fractures, and cancer therapy (vaccines), chronic liver disease and kidney failure.

Facilities at ISSL

Our Stem Cell Processing Centers

To deliver the best quality stem cells for your therapy, our dedicated cGMP compliant stem cell processing centers are equipped with state-of-the-art facilities, including clean rooms with class 100 work areas (the particle count is less than 100 particles/cubic foot of air) and cGMP quality assurance labs. All stem cell isolation procedures are performed by qualified and trained personnel with several years of experience in stem cell research and their clinical applications. We are proud to offer you the highest quality of service.

Our Therapy Centers

To ensure that you receive the best medical attention and service, we work with highly qualified doctors who are specialists in their field of medicine. All therapy regimens are performed in our well-equipped, world-class therapy center and specialist hospitals. Our therapy center is located in St. Theresa’s Hospital at Bangalore, India. In addition to state-of-the-art operating room and in-patient facilities, the center also houses the state-of-the-art Philips Endura C-arm with 1K2 imaging and BodySmart software, which allows the doctors to deliver stem cells directly and specifically to the site where they are needed. The C-arm also has a wide-ranging capabilities and allows multiple types of procedures including angiograms and embolisation.

All nervous system-related procedures are performed at Sita Bhateja Multispecialty Hospital in Bangalore, which is ranked among the best neuro-specialty hospitals in India.

Stem Cell Therapy

International Stem cell Services, in conjunction with International Stemcell Services, a world-leader in stem cell therapy, is happy to provide stem cell therapies for a number of diseases including osteoarthritis, peripheral vascular occlusion, myocardial infarcts, and spinal cord injury.

At International Stem cell Services, we are firmly committed to providing safe, effective and affordable stem cell therapy. From the beginning, we at International Stem cell Services have worked with highly qualified doctors who are experts in their fields of medicine to develop stem cell based therapy protocols for providing best stem cell treatment. Today, we are the only stem cell company in India with published scientific clinical data to prove the effectiveness and safety of our stem cell therapy.

Adult stem cell therapy to the rescue
Our adult stem cell treatment includes therapeutics efforts that are mainly centered on the use of adult stem cells that can be obtained from adult tissues such as bone marrow, umbilical cord, and cord blood. The use of adult stem cells for these adult stem cell therapy is known to be safe and does not have any ethical issues associated with it. Our adult stem cell treatments are done by highly qualified team of doctors.

Safe and effective stem cell treatment options
We work with highly qualified doctors who are experts in their fields and have developed stem cell-based therapies in a number of different disease areas. We collaborate with a number of top-level hospitals in India to provide state-of-the-art facilities for stem cell treatment. To date, we have successfully treated more than 100 patients using our stem cell-based approach. We provide stem cell therapy to you only after conducting extensive, scientifically sound clinical trials, the results of which are published in well known international journals. Therefore you can be assured of receiving the best treatment possible.

Stem cell Therapy is available for the following diseases:

• Late-stage peripheral vascular occlusion
• Diabetic foot ulcers
• Chronic liver failure
• Spinal cord injury
• Osteoarthritis
• Muscular dystrophy
• Myocardial infarction
• Cancer Therapy (Cancer Vaccines)

We are constantly working toward adding more diseases to the list of diseases that can be treated. If you have a condition that is not listed above, please contact us for a free consultation.

Stem Cell Banking

International Stem cell Services has been providing stem cell banking services for over 5 years in India and has over 25 years of experience in stem cell research. We are the only company who works as leading stem cell bank and provides efficient stem cell services in india. Our stem cell banking services includes harvesting and banking stem cells from all known sources including umbilical cord, cord blood, bone marrow and peripheral blood.

Stem cells obtained from the above-mentioned sources are called “adult stem cells”. These cells have enormous therapeutic potential and have been proven to be extremely beneficial in the treatment of several incurable diseases. Moreover, the use of adult stem cells is not hindered by ethical and scientific problems that presently confound the use of embryonic stem cells.

As ADULT STEM CELLS are able to transdifferentiate into other cell types we can exploit this feature for clinical therapy using stem cells.

Diseased conditions which can be treated by adult stem cells:

• Myocardial infarction
• Buerger’s Disease
• Osteo arthritis
• Diabetes
• Cancer therapy
• Liver Diseases
• Muscular dystrophy
• Acute Renal Failure

About ISSL

About Us

International Stem cell Services is a knowledge-based company, offering state-of-the-art stem cell banking facilities including stem cell therapies, stem cell banking, stem cell expansion, stem cell differentiation and many more. Founded in 2003, we are one of the oldest private cord blood banks in India. We are the first company in India to provide parents with the option of banking stem cells from cord blood as well as the umbilical cord itself. We are the only company in India to offer the highly specialized services of expansion of stem cell and stem cell differentiation and clinical application of stem cells.

One of the major aims of International Stem cell Services is to provide affordable adult stem cell treatment options for patients world-wide. We focus on producing superior quality of work backed with a strong scientific foundation. Our board of directors comprises people with more than three decades of experience in stem cell research. Our scientific advisory board consists of world-renowned researchers and clinicians who are experts in their field of medicine.

Mission

To provide safe, reliable, and affordable stem cell banking and therapy options to people world-wide.

Vision

International Stem cell Services aims to become the world-leader in providing stem cell banking, stem cell therapy services, stem cell expansion and differentiation of stem cell by focusing on improving technology, reducing costs and improving treatment outcomes.